Abstract:
Factors contributing to the development of fetal hypoxia are very numerous. Degree of immunehormonal
disorders depending on the severity of prenatal hypoxia has not been studied in detail. In this
study we investigated the localization of the activation marker CD27+peripheral blood lymphocytes and placenta
of rats with prenatal hypoxia of varying severity. Study the localization CD27+markers revealed disorders of
immune cells to the blood and placenta of rats during hypoxia of varying severity. Changes in CD cell
differentiation leads to functional immature T-lymphocytes. The study revealed violations of functional immune
parameters on systemic and local levels contribute to the pathological course of pregnancy and may result in
unfavorable outcome.
